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CasePlay: Self-Play Reinforcement Learning from Case Reports for Medical Reasoning

Hao Wang, Zihan Wang, Kai Wu, Jian Yao, Yiwen Ye, Yongcan Luo · Oct 18, 2026

Citations: 0

Match reason: Matched by broad semantic/index fallback.

Score: 45% Moderate protocol signal Freshness: Hot Status: Ready
Rubric Rating Automatic Metrics Medicine
  • To address these challenges, we propose CasePlay, a self-play framework with two key components: (a) a Knowledge-Conditioned Proposer, which anchors question generation to case-specific knowledge points so that questions draw on a broader…
  • Extensive experiments across seven medically related benchmarks demonstrate that CasePlay outperforms existing self-play baselines and improves the SFT warm-start model by 3.1 points on average, highlighted by a 6.3-point gain on LiveClin.
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