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HFEPX · Eval paper review

Agentic Personas for Adaptive Scientific Explanations with Knowledge Graphs

Susana Nunes, Tiago Guerreiro, Catia Pesquita

Published

Mar 23, 2026

Citations

0

Trust level

Low

Usefulness score

40/100 (Low)

Extraction confidence

45% (Low)

Derived from extracted protocol signals and abstract evidence.

Rater population

Domain Experts

Signals refreshed

Mar 23, 2026

Should you rely on this paper?

This paper is adjacent to HFEPX scope and is best used for background context, not as a primary protocol reference.

Use this as background context only. Do not make protocol decisions from this page alone.

Best use

Background context only

Use if you need

Background context only.

What to verify

Read the full paper before copying any benchmark, metric, or protocol choices.

Main weakness

The available metadata is too thin to trust this as a primary source.

Human feedback signal
Detected
From extracted signals
Evaluation signal
Weak or implicit
Validate from full paper
Usefulness for eval research
40/100
Adjacent candidate

Treat as adjacent context, not a core eval-method reference.

Abstract

AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts. Knowledge graph-based explanations, despite their capacity for grounded, path-based reasoning, inherit this limitation. In complex domains such as scientific discovery, this assumption fails to capture the diversity of cognitive strategies and epistemic stances among experts, preventing explanations that foster deeper understanding and informed decision-making. However, the scarcity of human experts limits the use of direct human feedback to produce adaptive explanations. We present a reinforcement learning approach for scientific explanation generation that incorporates agentic personas, structured representations of expert reasoning strategies, that guide the explanation agent towards specific epistemic preferences. In an evaluation of knowledge graph-based explanations for drug discovery, we tested two personas that capture distinct epistemic stances derived from expert feedback. Results show that persona-driven explanations match state-of-the-art predictive performance while persona preferences closely align with those of their corresponding experts. Adaptive explanations were consistently preferred over non-adaptive baselines (n = 22), and persona-based training reduces feedback requirements by two orders of magnitude. These findings demonstrate how agentic personas enable scalable adaptive explainability for AI systems in complex and high-stakes domains.

What we could verify

These are the protocol signals we could actually recover from the available paper metadata. Use them to decide whether this paper is worth deeper reading.

Human Feedback Types

partial

Pairwise Preference

Directly usable for protocol triage.

"AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts."

Evaluation Modes

missing

None explicit

Validate eval design from full paper text.

"AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts."

Quality Controls

missing

Not reported

No explicit QC controls found.

"AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts."

Benchmarks / Datasets

missing

Not extracted

No benchmark anchors detected.

"AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts."

Reported Metrics

missing

Not extracted

No metric anchors detected.

"AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts."

Rater Population

partial

Domain Experts

Helpful for staffing comparability.

"AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts."

Benchmarks and datasets

No benchmark or dataset names were extracted from the available abstract.

Reported metrics

No metric terms were extracted from the available abstract.

Human feedback details
Uses human feedback
Yes
Feedback types
Pairwise Preference
Rater population
Domain Experts
Expertise required
General
Evaluation details
Evaluation modes
None
Agentic eval
None
Quality controls
Not reported
Evidence quality
Low
Use this page as
Background context only

Research brief

Metadata summary

AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts.

Based on abstract + metadata only. Check the source paper before making high-confidence protocol decisions.

Key takeaways

  • AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts.
  • Knowledge graph-based explanations, despite their capacity for grounded, path-based reasoning, inherit this limitation.
  • In complex domains such as scientific discovery, this assumption fails to capture the diversity of cognitive strategies and epistemic stances among experts, preventing explanations that foster deeper understanding and informed decision-making.

Researcher actions

  • Compare this paper against nearby papers in the same arXiv category before using it for protocol decisions.
  • Check the full text for explicit evaluation design choices (raters, protocol, and metrics).
  • Use related-paper links to find stronger protocol-specific references.

Caveats

  • Generated from abstract + metadata only; no PDF parsing.
  • Signals below are heuristic and may miss details reported outside the abstract.

Contribution summary

  • However, the scarcity of human experts limits the use of direct human feedback to produce adaptive explanations.
  • We present a reinforcement learning approach for scientific explanation generation that incorporates agentic personas, structured representations of expert reasoning strategies, that guide the explanation agent towards specific epistemic…
  • In an evaluation of knowledge graph-based explanations for drug discovery, we tested two personas that capture distinct epistemic stances derived from expert feedback.

Why it matters for eval

  • However, the scarcity of human experts limits the use of direct human feedback to produce adaptive explanations.
  • We present a reinforcement learning approach for scientific explanation generation that incorporates agentic personas, structured representations of expert reasoning strategies, that guide the explanation agent towards specific epistemic…

Researcher checklist

  • Human feedback protocol is explicit

    Detected: Pairwise Preference

  • Evaluation mode is explicit

    No clear evaluation mode extracted.

  • Quality control reporting appears

    No calibration/adjudication/IAA control explicitly detected.

  • Benchmark or dataset anchors are present

    No benchmark/dataset anchor extracted from abstract.

  • Metric reporting is present

    No metric terms extracted.