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HFEPX · Eval paper review

KlinikeBench: Evaluating Language Models Beyond Diagnostic Accuracy

Xueting Fang, Zehui Li, Yang Yang, Camilla Giovino +4 more

Published

Sep 29, 2026

Citations

0

Trust level

High

Usefulness score

65/100 (Medium)

Extraction confidence

80% (High)

Derived from extracted protocol signals and abstract evidence.

Rater population

Domain Experts

Signals refreshed

Oct 6, 2026

Should you rely on this paper?

This paper has useful evaluation signal, but protocol completeness is partial; pair it with related papers before deciding implementation strategy.

Use this as a practical starting point for protocol research, then validate against the original paper.

Best use

Secondary protocol comparison source

Use if you need

A benchmark-and-metrics comparison anchor.

What to verify

Validate the evaluation procedure and quality controls in the full paper before operational use.

Main weakness

No major weakness surfaced.

Human feedback signal
Detected
From extracted signals
Evaluation signal
Detected
Eval setup described
Usefulness for eval research
65/100
Moderate-confidence candidate

Useful as a secondary reference; validate protocol details against neighboring papers.

Abstract

Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions. In clinical practice, however, patients present information in different ways, and clinicians must obtain relevant history and determine which examinations are needed before reaching a diagnosis. Diagnostic accuracy alone therefore cannot establish whether an agent gathered essential information or conducted an appropriate clinical assessment. Furthermore, existing benchmarks lack professional clinicians' verification. To address this gap, we introduce KlinikeBench, a benchmark of 333 clinician-authored tasks, each providing an isolated sandbox environment with a virtual patient, clinical tools, and task-specific success criteria. More than 35 clinicians contributed to case authoring and benchmark evaluation. In an empirical study, clinicians gave simulated dialogues higher mean quality ratings than reference conversations, which is adapted from real conversation. In each task, an LM has a fixed budget of turns to communicate with the patient, ask about relevant history, request examinations, follow action constraints, and record a final diagnosis. We score these steps separately as well as together. Across 31 models and seven model families, the best-performing models (e.g., GPT-6-astra and Claude Opus 5) succeed on less than 30% of tasks, even though their diagnosis accuracy reaches 90.7%. Some models benefit from talking with the patient; others diagnose well from a complete chart but perform much worse in conversation. Overall, KlinikeBench provides a testbed for evaluating the full clinical encounter and reveals a substantial gap between diagnostic accuracy and performance in interactive clinical assessment. All the code and data is available on https://zehui127.github.io/klinikebench/

What we could verify

These are the protocol signals we could actually recover from the available paper metadata. Use them to decide whether this paper is worth deeper reading.

Human Feedback Types

strong

Expert Verification

Directly usable for protocol triage.

"Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions."

Evaluation Modes

strong

Automatic Metrics

Includes extracted eval setup.

"Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions."

Quality Controls

missing

Not reported

No explicit QC controls found.

"Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions."

Benchmarks / Datasets

strong

Klinikebench

Useful for quick benchmark comparison.

"To address this gap, we introduce KlinikeBench, a benchmark of 333 clinician-authored tasks, each providing an isolated sandbox environment with a virtual patient, clinical tools, and task-specific success criteria."

Reported Metrics

strong

Accuracy

Useful for evaluation criteria comparison.

"Diagnostic accuracy alone therefore cannot establish whether an agent gathered essential information or conducted an appropriate clinical assessment."

Rater Population

strong

Domain Experts

Helpful for staffing comparability.

"Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions."

Benchmarks and datasets

Klinikebench

Reported metrics

accuracy
Human feedback details
Uses human feedback
Yes
Feedback types
Expert Verification
Rater population
Domain Experts
Expertise required
Medicine, Coding
Evaluation details
Evaluation modes
Automatic Metrics
Agentic eval
None
Quality controls
Not reported
Evidence quality
High
Use this page as
Secondary protocol comparison source

Research brief

Metadata summary

Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions.

Based on abstract + metadata only. Check the source paper before making high-confidence protocol decisions.

Key takeaways

  • Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions.
  • In clinical practice, however, patients present information in different ways, and clinicians must obtain relevant history and determine which examinations are needed before reaching a diagnosis.
  • Diagnostic accuracy alone therefore cannot establish whether an agent gathered essential information or conducted an appropriate clinical assessment.

Researcher actions

  • Compare this paper against nearby papers in the same arXiv category before using it for protocol decisions.
  • Validate inferred eval signals (Automatic metrics, Simulation environment) against the full paper.
  • Use related-paper links to find stronger protocol-specific references.

Caveats

  • Generated from abstract + metadata only; no PDF parsing.
  • Signals below are heuristic and may miss details reported outside the abstract.

Recommended queries

Contribution summary

  • Most clinical benchmarks evaluate language models (LMs) on diagnosis using complete case descriptions.
  • Diagnostic accuracy alone therefore cannot establish whether an agent gathered essential information or conducted an appropriate clinical assessment.
  • To address this gap, we introduce KlinikeBench, a benchmark of 333 clinician-authored tasks, each providing an isolated sandbox environment with a virtual patient, clinical tools, and task-specific success criteria.

Why it matters for eval

  • Diagnostic accuracy alone therefore cannot establish whether an agent gathered essential information or conducted an appropriate clinical assessment.
  • To address this gap, we introduce KlinikeBench, a benchmark of 333 clinician-authored tasks, each providing an isolated sandbox environment with a virtual patient, clinical tools, and task-specific success criteria.

Researcher checklist

  • Human feedback protocol is explicit

    Detected: Expert Verification

  • Evaluation mode is explicit

    Detected: Automatic Metrics

  • Quality control reporting appears

    No calibration/adjudication/IAA control explicitly detected.

  • Benchmark or dataset anchors are present

    Detected: Klinikebench

  • Metric reporting is present

    Detected: accuracy