DNA Nanotechnology Expert — Problem Author & Evaluator

About OpenTrain

OpenTrain is the #1 platform for people building careers in AI training and data labeling. We connect experts with projects that shape how cutting-edge AI systems learn, and we help contributors build a single, verifiable portfolio of AI training work.

As a contributor you control your profile, discover projects that match your skills, and turn short-term gigs into long-term expertise in the fast-growing field of AI training.

• Work fully remote and manage opportunities in one place.
• Build a durable portfolio of AI-training contributions that shows real technical skill.

About AI training work

AI training (also called data labeling or human feedback work) is the human side of building AI: people create and evaluate examples that teach models how to reason, generate text, and solve domain problems. This role focuses on expert-level problem authoring and evaluation for generative models.

Many projects are flexible and part-time, and they let domain experts directly influence model behavior and accuracy in specialized fields.

• This work combines domain expertise with clear written rationale and careful evaluation of model outputs.
• Typical tasks include authoring high-quality prompts/problems, grading model responses, and providing detailed corrections.

The role — DNA Nanotechnology Expert

OpenTrain is hiring DNA nanotechnology experts to author and review challenging structural DNA problems and to evaluate AI-generated solutions for correctness and rigor. You will create problems in DNA origami, nucleic-acid nanostructures, strand-displacement systems, and sequence or structure design, and you will provide thorough written justification for assessments.

This is a contractor, part-time role (20+ hours/week) paid per hour at $75 USD. Work may be done from anywhere; English is required for task instructions and written rationale.

• Label types: TEXT_GENERATION and EVALUATION_RATING (authoring prompts/problems and rating model outputs).
• Employment: Contractor, Part-time; worldwide applicants accepted.

What you'll do

Your day-to-day tasks focus on designing rigorous, expert-level problems and assessing AI answers with precise scientific judgment and clear written feedback.

• Design expert-level problems covering DNA origami, nucleic-acid nanostructures, strand-displacement systems, and sequence or structure design.
• Review peer-authored problems for clarity, difficulty, and ground-truth correctness.
• Evaluate AI-generated solutions and compare model outputs with detailed written justification.
• Provide meticulous scientific reasoning and document any errors, pitfalls, or ambiguity in model responses.

Requirements

You must have advanced research experience and hands-on familiarity with structural nucleic-acid design tools and methods. Strong scientific writing and attention to detail are essential.

• PhD or equivalent research experience in chemistry, bioengineering, biophysics, or a related field focused on DNA or nucleic-acid nanotechnology.
• Hands-on experience with DNA origami, structural nucleic-acid design, or molecular self-assembly.
• Familiarity with caDNAno, oxDNA, or NUPACK.
• Proven ability to judge correctness and rigor in scientific problem solving; strong technical writing and detailed rationale.
• Availability for 20+ hours per week and fluency in English.

Who should apply

This role is ideal for researchers and practitioners who want to apply their DNA nanotechnology expertise to improve how AI systems reason about molecular design. If you enjoy crafting precise problems, spotting subtle errors, and writing clear scientific explanations, this project fits you.

• Experienced academics, postdocs, or industry scientists with hands-on DNA nanotech experience.
• People who can translate complex technical knowledge into unambiguous, testable problems and thorough model critiques.
• Contributors who prefer flexible, remote contract work and want to build an OpenTrain portfolio.

How it works & compensation

OpenTrain contributors create a free profile, discover projects, and apply. If selected you'll be engaged as a contractor and assigned tasks that match your expertise. Deliverables include authored problems, peer reviews, and written evaluations of AI outputs.

This role pays $75 USD per hour on a contractor basis. Expected time commitment is 20+ hours per week; exact scheduling is flexible within the project's needs.

• Pay type: Pay per hour — $75 USD/hour.
• Time commitment: 20+ hours per week; part-time contractor.
• Work is task-based: author problems, review peers, and evaluate model outputs with written justification.