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FHIRPath-QA: Executable Question Answering over FHIR Electronic Health Records

Michael Frew, Nishit Bheda, Bryan Tripp · Feb 26, 2026 · Citations: 0

How to use this page

Low trust

Use this as background context only. Do not make protocol decisions from this page alone.

Best use

Background context only

What to verify

Read the full paper before copying any benchmark, metric, or protocol choices.

Evidence quality

Low

Derived from extracted protocol signals and abstract evidence.

Abstract

Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions. Large language models (LLM) show promise in clinical question answering (QA), but retrieval-based approaches are computationally inefficient, prone to hallucination, and difficult to deploy over real-life EHRs. This work introduces FHIRPath-QA, the first open dataset and benchmark for patient-specific QA that includes open-standard FHIRPath queries over real-world clinical data. A text-to-FHIRPath QA paradigm is proposed that shifts reasoning from free-text generation to FHIRPath query synthesis. For o4-mini, this reduced average token usage by 391x relative to retrieval-first prompting (629,829 vs 1,609 tokens per question) and lowered failure rates from 0.36 to 0.09 on clinician-phrased questions. Built on MIMIC-IV on FHIR Demo, the dataset pairs over 14k natural language questions in patient and clinician phrasing with validated FHIRPath queries and answers. Empirically, the evaluated LLMs achieve at most 42% accuracy, highlighting the challenge of the task, but benefit strongly from supervised fine-tuning, with query synthesis accuracy improving from 27% to 79% for 4o-mini. These results highlight that text-to-FHIRPath synthesis has the potential to serve as a practical foundation for safe, efficient, and interoperable consumer health applications, and the FHIRPath-QA dataset and benchmark serve as a starting point for future research on the topic. The full dataset and generation code can be accessed at: https://github.com/mooshifrew/fhirpath-qa.

Low-signal caution for protocol decisions

Use this page for context, then validate protocol choices against stronger HFEPX references before implementation decisions.

  • The available metadata is too thin to trust this as a primary source.
  • The abstract does not clearly describe the evaluation setup.
  • The abstract does not clearly name benchmarks or metrics.

Should You Rely On This Paper?

This paper is adjacent to HFEPX scope and is best used for background context, not as a primary protocol reference.

Best use

Background context only

Use if you need

Background context only.

Main weakness

The available metadata is too thin to trust this as a primary source.

Trust level

Low

Usefulness score

40/100 • Low

Treat as adjacent context, not a core eval-method reference.

Human Feedback Signal

Detected

Evaluation Signal

Weak / implicit signal

Usefulness for eval research

Adjacent candidate

Extraction confidence 45%

What We Could Verify

These are the protocol signals we could actually recover from the available paper metadata. Use them to decide whether this paper is worth deeper reading.

Human Feedback Types

partial

Expert Verification

Directly usable for protocol triage.

"Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions."

Evaluation Modes

missing

None explicit

Validate eval design from full paper text.

"Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions."

Quality Controls

missing

Not reported

No explicit QC controls found.

"Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions."

Benchmarks / Datasets

missing

Not extracted

No benchmark anchors detected.

"Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions."

Reported Metrics

missing

Not extracted

No metric anchors detected.

"Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions."

Rater Population

partial

Domain Experts

Helpful for staffing comparability.

"Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions."

Human Feedback Details

  • Uses human feedback: Yes
  • Feedback types: Expert Verification
  • Rater population: Domain Experts
  • Expertise required: Medicine, Coding

Evaluation Details

  • Evaluation modes:
  • Agentic eval: None
  • Quality controls: Not reported
  • Evidence quality: Low
  • Use this page as: Background context only

Protocol And Measurement Signals

Benchmarks / Datasets

No benchmark or dataset names were extracted from the available abstract.

Reported Metrics

No metric terms were extracted from the available abstract.

Research Brief

Metadata summary

Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions.

Based on abstract + metadata only. Check the source paper before making high-confidence protocol decisions.

Key Takeaways

  • Though patients are increasingly granted digital access to their electronic health records (EHRs), existing interfaces may not support precise, trustworthy answers to patient-specific questions.
  • Large language models (LLM) show promise in clinical question answering (QA), but retrieval-based approaches are computationally inefficient, prone to hallucination, and difficult to deploy over real-life EHRs.
  • This work introduces FHIRPath-QA, the first open dataset and benchmark for patient-specific QA that includes open-standard FHIRPath queries over real-world clinical data.

Researcher Actions

  • Compare this paper against nearby papers in the same arXiv category before using it for protocol decisions.
  • Validate inferred eval signals (Automatic metrics) against the full paper.
  • Use related-paper links to find stronger protocol-specific references.

Caveats

  • Generated from abstract + metadata only; no PDF parsing.
  • Signals below are heuristic and may miss details reported outside the abstract.

Recommended Queries

Research Summary

Contribution Summary

  • In this work, we introduce FHIRPath-QA, the first open dataset and benchmark for patient-specific QA that includes open-standard FHIRPath queries over real-world clinical data.
  • We propose a text-to-FHIRPath QA paradigm that shifts reasoning from free-text generation to FHIRPath query synthesis, significantly reducing LLM usage.
  • Further, we demonstrate that state-of-the-art LLMs struggle to deal with ambiguity in patient language and perform poorly in FHIRPath query synthesis.

Why It Matters For Eval

  • In this work, we introduce FHIRPath-QA, the first open dataset and benchmark for patient-specific QA that includes open-standard FHIRPath queries over real-world clinical data.
  • Our results highlight that text-to-FHIRPath synthesis has the potential to serve as a practical foundation for safe, efficient, and interoperable consumer health applications, and our dataset and benchmark serve as a starting point for…

Researcher Checklist

  • Pass: Human feedback protocol is explicit

    Detected: Expert Verification

  • Gap: Evaluation mode is explicit

    No clear evaluation mode extracted.

  • Gap: Quality control reporting appears

    No calibration/adjudication/IAA control explicitly detected.

  • Gap: Benchmark or dataset anchors are present

    No benchmark/dataset anchor extracted from abstract.

  • Gap: Metric reporting is present

    No metric terms extracted.

Related Papers

Papers are ranked by protocol overlap, extraction signal alignment, and semantic proximity.

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