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HFEPX · Eval paper review

When Documents Disagree: Measuring Institutional Variation in Transplant Guidance with Retrieval-Augmented Language Models

Yubo Li, Ramayya Krishnan, Rema Padman

Published

Mar 23, 2026

Citations

0

Trust level

Low

Usefulness score

40/100 (Low)

Extraction confidence

45% (Low)

Derived from extracted protocol signals and abstract evidence.

Rater population

Not reported

Signals refreshed

Mar 23, 2026

Should you rely on this paper?

This paper is adjacent to HFEPX scope and is best used for background context, not as a primary protocol reference.

Use this as background context only. Do not make protocol decisions from this page alone.

Best use

Background context only

Use if you need

Background context only.

What to verify

Read the full paper before copying any benchmark, metric, or protocol choices.

Main weakness

The available metadata is too thin to trust this as a primary source.

Human feedback signal
Detected
From extracted signals
Evaluation signal
Weak or implicit
Validate from full paper
Usefulness for eval research
40/100
Adjacent candidate

Treat as adjacent context, not a core eval-method reference.

Abstract

Patient education materials for solid-organ transplantation vary substantially across U.S. centers, yet no systematic method exists to quantify this heterogeneity at scale. We introduce a framework that grounds the same patient questions in different centers' handbooks using retrieval-augmented language models and compares the resulting answers using a five-label consistency taxonomy. Applied to 102 handbooks from 23 centers and 1,115 benchmark questions, the framework quantifies heterogeneity across four dimensions: question, topic, organ, and center. We find that 20.8% of non-absent pairwise comparisons exhibit clinically meaningful divergence, concentrated in condition monitoring and lifestyle topics. Coverage gaps are even more prominent: 96.2% of question-handbook pairs miss relevant content, with reproductive health at 95.1% absence. Center-level divergence profiles are stable and interpretable, where heterogeneity reflects systematic institutional differences, likely due to patient diversity. These findings expose an information gap in transplant patient education materials, with document-grounded medical question answering highlighting opportunities for content improvement.

What we could verify

These are the protocol signals we could actually recover from the available paper metadata. Use them to decide whether this paper is worth deeper reading.

Human Feedback Types

partial

Pairwise Preference

Directly usable for protocol triage.

"Patient education materials for solid-organ transplantation vary substantially across U.S."

Evaluation Modes

missing

None explicit

Validate eval design from full paper text.

"Patient education materials for solid-organ transplantation vary substantially across U.S."

Quality Controls

missing

Not reported

No explicit QC controls found.

"Patient education materials for solid-organ transplantation vary substantially across U.S."

Benchmarks / Datasets

missing

Not extracted

No benchmark anchors detected.

"Patient education materials for solid-organ transplantation vary substantially across U.S."

Reported Metrics

missing

Not extracted

No metric anchors detected.

"Patient education materials for solid-organ transplantation vary substantially across U.S."

Benchmarks and datasets

No benchmark or dataset names were extracted from the available abstract.

Reported metrics

No metric terms were extracted from the available abstract.

Human feedback details
Uses human feedback
Yes
Feedback types
Pairwise Preference
Rater population
Not reported
Unit of annotation
Pairwise (inferred)
Expertise required
Medicine
Evaluation details
Evaluation modes
None
Agentic eval
None
Quality controls
Not reported
Evidence quality
Low
Use this page as
Background context only

Research brief

Metadata summary

Patient education materials for solid-organ transplantation vary substantially across U.S.

Based on abstract + metadata only. Check the source paper before making high-confidence protocol decisions.

Key takeaways

  • Patient education materials for solid-organ transplantation vary substantially across U.S.
  • centers, yet no systematic method exists to quantify this heterogeneity at scale.
  • We introduce a framework that grounds the same patient questions in different centers' handbooks using retrieval-augmented language models and compares the resulting answers using a five-label consistency taxonomy.

Researcher actions

  • Compare this paper against nearby papers in the same arXiv category before using it for protocol decisions.
  • Check the full text for explicit evaluation design choices (raters, protocol, and metrics).
  • Use related-paper links to find stronger protocol-specific references.

Caveats

  • Generated from abstract + metadata only; no PDF parsing.
  • Signals below are heuristic and may miss details reported outside the abstract.

Contribution summary

  • We introduce a framework that grounds the same patient questions in different centers' handbooks using retrieval-augmented language models and compares the resulting answers using a five-label consistency taxonomy.
  • Applied to 102 handbooks from 23 centers and 1,115 benchmark questions, the framework quantifies heterogeneity across four dimensions: question, topic, organ, and center.
  • We find that 20.8% of non-absent pairwise comparisons exhibit clinically meaningful divergence, concentrated in condition monitoring and lifestyle topics.

Why it matters for eval

  • Applied to 102 handbooks from 23 centers and 1,115 benchmark questions, the framework quantifies heterogeneity across four dimensions: question, topic, organ, and center.

Researcher checklist

  • Human feedback protocol is explicit

    Detected: Pairwise Preference

  • Evaluation mode is explicit

    No clear evaluation mode extracted.

  • Quality control reporting appears

    No calibration/adjudication/IAA control explicitly detected.

  • Benchmark or dataset anchors are present

    No benchmark/dataset anchor extracted from abstract.

  • Metric reporting is present

    No metric terms extracted.