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SAGE: Shape-Adapting Gated Experts for Adaptive Histopathology Image Segmentation

Gia Huy Thai, Hoang-Nguyen Vu, Anh-Minh Phan, Quang-Thinh Ly, Tram Dinh, Thi-Ngoc-Truc Nguyen, Nhat Ho · Nov 23, 2025 · Citations: 0

How to use this page

Low trust

Use this as background context only. Do not make protocol decisions from this page alone.

Best use

Background context only

What to verify

Validate the evaluation procedure and quality controls in the full paper before operational use.

Evidence quality

Low

Derived from extracted protocol signals and abstract evidence.

Abstract

The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity. Current CNN-Transformer hybrids use static computation graphs with fixed routing. This leads to extra computation and makes it harder to adapt to changes in input. We propose Shape-Adapting Gated Experts (SAGE), an input-adaptive framework that enables dynamic expert routing in heterogeneous visual networks. SAGE reconfigures static backbones into dynamically routed expert architectures via a dual-path design with hierarchical gating and a Shape-Adapting Hub (SA-Hub) that harmonizes feature representations across convolutional and transformer modules. Embodied as SAGE with ConvNeXt and Vision Transformer UNet (SAGE-ConvNeXt+ViT-UNet), our model achieves a Dice score of 95.23\% on EBHI, 92.78\%/91.42\% DSC on GlaS Test A/Test B, and 91.26\% DSC at the WSI level on DigestPath, while exhibiting robust generalization under distribution shifts by adaptively balancing local refinement and global context. SAGE establishes a scalable foundation for dynamic expert routing in visual networks, thereby facilitating flexible visual reasoning.

Abstract-only analysis — low confidence

All signals on this page are inferred from the abstract only and may be inaccurate. Do not use this page as a primary protocol reference.

  • This paper looks adjacent to evaluation work, but not like a strong protocol reference.
  • The available metadata is too thin to trust this as a primary source.

Should You Rely On This Paper?

This paper is adjacent to HFEPX scope and is best used for background context, not as a primary protocol reference.

Best use

Background context only

Use if you need

A secondary eval reference to pair with stronger protocol papers.

Main weakness

This paper looks adjacent to evaluation work, but not like a strong protocol reference.

Trust level

Low

Usefulness score

0/100 • Low

Treat as adjacent context, not a core eval-method reference.

Human Feedback Signal

Not explicit in abstract metadata

Evaluation Signal

Detected

Usefulness for eval research

Adjacent candidate

Extraction confidence 35%

What We Could Verify

These are the protocol signals we could actually recover from the available paper metadata. Use them to decide whether this paper is worth deeper reading.

Human Feedback Types

missing

None explicit

No explicit feedback protocol extracted.

"The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity."

Evaluation Modes

partial

Automatic Metrics

Includes extracted eval setup.

"The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity."

Quality Controls

missing

Not reported

No explicit QC controls found.

"The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity."

Benchmarks / Datasets

missing

Not extracted

No benchmark anchors detected.

"The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity."

Reported Metrics

partial

Dice

Useful for evaluation criteria comparison.

"Embodied as SAGE with ConvNeXt and Vision Transformer UNet (SAGE-ConvNeXt+ViT-UNet), our model achieves a Dice score of 95.23\% on EBHI, 92.78\%/91.42\% DSC on GlaS Test A/Test B, and 91.26\% DSC at the WSI level on DigestPath, while exhibiting robust generalization under distribution shifts by adaptively balancing local refinement and global context."

Rater Population

partial

Domain Experts

Helpful for staffing comparability.

"We propose Shape-Adapting Gated Experts (SAGE), an input-adaptive framework that enables dynamic expert routing in heterogeneous visual networks."

Human Feedback Details

  • Uses human feedback: No
  • Feedback types: None
  • Rater population: Domain Experts
  • Expertise required: General

Evaluation Details

  • Evaluation modes: Automatic Metrics
  • Agentic eval: None
  • Quality controls: Not reported
  • Evidence quality: Low
  • Use this page as: Background context only

Protocol And Measurement Signals

Benchmarks / Datasets

No benchmark or dataset names were extracted from the available abstract.

Reported Metrics

dice

Research Brief

Metadata summary

The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity.

Based on abstract + metadata only. Check the source paper before making high-confidence protocol decisions.

Key Takeaways

  • The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity.
  • Current CNN-Transformer hybrids use static computation graphs with fixed routing.
  • This leads to extra computation and makes it harder to adapt to changes in input.

Researcher Actions

  • Compare this paper against nearby papers in the same arXiv category before using it for protocol decisions.
  • Check the full text for explicit evaluation design choices (raters, protocol, and metrics).
  • Use related-paper links to find stronger protocol-specific references.

Caveats

  • Generated from abstract + metadata only; no PDF parsing.
  • Signals below are heuristic and may miss details reported outside the abstract.

Research Summary

Contribution Summary

  • We propose Shape-Adapting Gated Experts (SAGE), an input-adaptive framework that enables dynamic expert routing in heterogeneous visual networks.

Why It Matters For Eval

  • Abstract shows limited direct human-feedback or evaluation-protocol detail; use as adjacent methodological context.

Researcher Checklist

  • Gap: Human feedback protocol is explicit

    No explicit human feedback protocol detected.

  • Pass: Evaluation mode is explicit

    Detected: Automatic Metrics

  • Gap: Quality control reporting appears

    No calibration/adjudication/IAA control explicitly detected.

  • Gap: Benchmark or dataset anchors are present

    No benchmark/dataset anchor extracted from abstract.

  • Pass: Metric reporting is present

    Detected: dice

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Papers are ranked by protocol overlap, extraction signal alignment, and semantic proximity.

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