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HFEPX · Eval paper review

Narrative Feature or Structured Feature? A Study of Large Language Models to Identify Cancer Patients at Risk of Heart Failure

Ziyi Chen, Mengyuan Zhang, Mustafa Mohammed Ahmed, Yi Guo +3 more

Published

Mar 18, 2024

Citations

0

Trust level

Low

Usefulness score

0/100 (Low)

Extraction confidence

35% (Low)

Derived from extracted protocol signals and abstract evidence.

Rater population

Not reported

Signals refreshed

Jun 24, 2026

Should you rely on this paper?

This paper is adjacent to HFEPX scope and is best used for background context, not as a primary protocol reference.

Use this as background context only. Do not make protocol decisions from this page alone.

Best use

Background context only

Use if you need

A secondary eval reference to pair with stronger protocol papers.

What to verify

Validate the evaluation procedure and quality controls in the full paper before operational use.

Main weakness

This paper looks adjacent to evaluation work, but not like a strong protocol reference.

Human feedback signal
Not explicit
Not explicit in abstract metadata
Evaluation signal
Detected
Eval setup described
Usefulness for eval research
0/100
Adjacent candidate

Treat as adjacent context, not a core eval-method reference.

Abstract

Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship. Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety. This study examined machine learning (ML) models to identify cancer patients at risk of HF using electronic health records (EHRs), including traditional ML, Time-Aware long short-term memory (T-LSTM), and large language models (LLMs) using novel narrative features derived from the structured medical codes. We identified a cancer cohort of 12,806 patients from the University of Florida Health, diagnosed with lung, breast, and colorectal cancers, among which 1,602 individuals developed HF after cancer. The LLM, GatorTron-3.9B, achieved the best F1 scores, outperforming the traditional support vector machines by 39%, the T-LSTM deep learning model by 7%, and a widely used transformer model, BERT, by 5.6%. The analysis shows that the proposed narrative features remarkably increased feature density and improved performance.

What we could verify

These are the protocol signals we could actually recover from the available paper metadata. Use them to decide whether this paper is worth deeper reading.

Human Feedback Types

missing

None explicit

No explicit feedback protocol extracted.

"Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship."

Evaluation Modes

partial

Automatic Metrics

Includes extracted eval setup.

"Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship."

Quality Controls

missing

Not reported

No explicit QC controls found.

"Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship."

Benchmarks / Datasets

missing

Not extracted

No benchmark anchors detected.

"Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship."

Reported Metrics

partial

F1

Useful for evaluation criteria comparison.

"Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship."

Benchmarks and datasets

No benchmark or dataset names were extracted from the available abstract.

Reported metrics

f1
Human feedback details
Uses human feedback
No
Feedback types
None
Rater population
Not reported
Expertise required
Medicine
Evaluation details
Evaluation modes
Automatic Metrics
Agentic eval
None
Quality controls
Not reported
Evidence quality
Low
Use this page as
Background context only

Research brief

Metadata summary

Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship.

Based on abstract + metadata only. Check the source paper before making high-confidence protocol decisions.

Key takeaways

  • Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship.
  • Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety.
  • This study examined machine learning (ML) models to identify cancer patients at risk of HF using electronic health records (EHRs), including traditional ML, Time-Aware long short-term memory (T-LSTM), and large language models (LLMs) using novel narrative features derived from the structured medical codes.

Researcher actions

  • Compare this paper against nearby papers in the same arXiv category before using it for protocol decisions.
  • Validate inferred eval signals (Automatic metrics) against the full paper.
  • Use related-paper links to find stronger protocol-specific references.

Caveats

  • Generated from abstract + metadata only; no PDF parsing.
  • Signals below are heuristic and may miss details reported outside the abstract.

Recommended queries

Contribution summary

  • Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety.
  • The LLM, GatorTron-3.9B, achieved the best F1 scores, outperforming the traditional support vector machines by 39%, the T-LSTM deep learning model by 7%, and a widely used transformer model, BERT, by 5.6%.

Why it matters for eval

  • Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety.

Researcher checklist

  • Human feedback protocol is explicit

    No explicit human feedback protocol detected.

  • Evaluation mode is explicit

    Detected: Automatic Metrics

  • Quality control reporting appears

    No calibration/adjudication/IAA control explicitly detected.

  • Benchmark or dataset anchors are present

    No benchmark/dataset anchor extracted from abstract.

  • Metric reporting is present

    Detected: f1