CogGen: Cognitive-Load-Informed Fully Unsupervised Deep Generative Modeling for Compressively Sampled MRI Reconstruction

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Abstract

Fully unsupervised deep generative modeling (FU-DGM) is promising for compressively sampled MRI (CS-MRI) when training data or compute are limited. Classical FU-DGMs such as DIP and INR rely on architectural priors, but the ill-conditioned inverse problem often demands many iterations and easily overfits measurement noise. We propose CogGen, a cognitive-load-informed FU-DGM that casts CS-MRI as staged inversion and regulates task-side "cognitive load" by progressively scheduling intrinsic difficulty and extraneous interference. CogGen replaces uniform data fitting with an easy-to-hard k-space weighting/selection strategy: early iterations emphasize low-frequency, high-SNR, structure-dominant samples, while higher-frequency or noise-dominated measurements are introduced later. We realize this schedule through self-paced curriculum learning (SPCL) with complementary criteria: a student mode that reflects what the model can currently learn and a teacher mode that indicates what it should follow, supporting both soft weighting and hard selection. Experiments and analyses show that CogGen-DIP and CogGen-INR improve reconstruction fidelity and convergence behavior compared with strong unsupervised baselines and competitive supervised pipelines.